Kaizer Chiefs and Bloemfontein Celtic have been drawn together in the pick of the Nedbank Cup quarter-finals following the draw on Monday.
Amakhosi booked their place in the last-eight with a convincing 3-0 win over PSL rivals Bidvest Wits, and have been rewarded with a clash against Siwelele, who saw off provincial rivals Free State Stars this weekend.
Another all-Premier Soccer League clash sees Mamelodi Sundowns take on Platinum Stars, while there is also an all-National First Division tie, with United FC hosting African Warriors.
Defending champions SuperSport United still have to wait to learn the identity of their quarter-final opponent, with Tembu Royals and Maritzburg United still having to contest their last-16 encounter.
The tie, which was initially scheduled for this past Sunday, was postponed as AmaZulu had protested against the eligibility of a player fielded by Royals in their shock last-32 win over Usuthu.
That case has since been dismissed and the last-16 clash, as well as the quarter-final times, dates and venues, are still to be confirmed by the PSL.
Tembu Royals FC/Maritzburg United v SuperSport United
Mamelodi Sundowns v Platinum Stars
United FC v African Warriors
Bloemfontein Celtic v Kaizer Chiefs